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Original Article
Serum Nitric Oxide and Tumor Necrosis Factor-α Levels in Patients with Kawasaki Disease
Ji Hye Park, Jee Seon Shin, Young Mi Hong
Clin Exp Pediatr. 2005;48(7):772-778.   Published online July 15, 2005
Purpose : Kawasaki disease(KD) is a systemic panvasculitis that causes coronary artery lesions. KD is accompanied by immunoregulatory abnormalities. Nitric oxide(NO) can induce relaxation of blood vessels by activating guanylate cyclase in smooth muscle cells and high levels of NO may result in coronary artery lesions. We investigated tumor necrosis factor(TNF)-α and NO production before and after intravenous immunoglobulin(IVIG) therapy...
Pulmonary Function Test and Body Composition Analysis in Obese Children
Jee Seon Shin, Ji Hye Park, Ji Young Kim, Su Jung Kim, Young Mi Hong
Clin Exp Pediatr. 2005;48(6):588-593.   Published online June 15, 2005
Purpose : Obesity is associated with disturbances of ventilatory functions in adults. But few studies have evaluated the pulmonary complications of obesity in the pediatric population. The purpose of this study is to clarify the effects of obesity on pulmonary function and body composition in obese children. Methods : Forty seven obese children whose ages ranged from nine to twelve...
Benign Transient Hyperphosphatasemia of Infancy and Childhood
Jung Hyun Kwon, Ji Hye Park, Hae Soon Kim, Seung Joo Lee, Mi Ae Lee
Clin Exp Pediatr. 2005;48(3):306-309.   Published online March 15, 2005
Purpose : The aim of study is to investigate the clinical manifestations and the etiology of markedly-elevated serum alkaline phosphatase(ALP) levels in children without accompanying liver or bone disease. Methods : The serum ALP and other biochemical laboratory data of 4,989 patients attending the pediatric department of Ewha Womans University Mokdong Hospital between January 2002 to December 2002 were studied. The...
Functional Antibody Responses to Seven Serotypes in Pneumococcal Polysaccharide Vaccine in Children
Ji Hye Park, Hee Jung Kim, Young Mi Hong, Kyung Hyo Kim
Clin Exp Pediatr. 2004;47(11):1173-1180.   Published online November 15, 2004
Purpose : Streptococcus pneumoniae is an important pathogen in children as well as in elderly people. The aim of this study was to assess the opsonization activity of pneumococal capsular antibody to seven serotypes in 23-valent pneumococcal polysaccharide vaccine before and after immunization in Korean children. Methods : Nine children from 24 to 49 months of age were immunized with 23-valent...
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